Advisers against you replacing setter with new rogue (5,5)
I believe the answer is:
agony aunts
'advisers' is the definition.
(I've seen this before)
'against you replacing setter with new rogue' is the wordplay.
I cannot quite see how this works, but
'against' could be 'on' (on can mean by or up against) and 'on' is found in the answer.
'you' could be 'ya' (non-standard spelling as in 'see ya later') and 'ya' is located in the answer.
'new' could be 'n' (common abbreviation eg NT for New Testament) and 'n' is located in the answer.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for agony aunts that I've seen before include "people who have problems to deal with?" , "Advice columnists" , "Write to these for advice" , "Advisers" , "Columnists advising" .)