Alienated (9)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">alienated</span>' is the definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for estranged that I've seen before include "Alienated, disaffected" , "no longer friendly" , "Sad regent (anag) - disaffected" , "Having become unfriendly or alienated" , "Cut off" .)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">alienated</span>' is the definition.<br/ ><span class="explanation-format__explanation">('disaffect' can be a synonym of 'alienate')</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for disaffected that I've seen before include "Out of sympathy with those in power" , "Rebellious" , "No longer supporting those in power" , "Alienated from authority" , "No longer willing to support those in authority" .)