Blasts waste by son (5)
I believe the answer is:
blows
'blasts' is the definition.
('blow' can be a synonym of 'blast')
'waste by son' is the wordplay.
'waste' becomes 'blow' (synonyms).
'by son' becomes 's' (genealogical abbreviation for son. I am not sure about the 'by' bit.).
'blow'+'s'='BLOWS'
Can you help me to learn more?
(Other definitions for blows that I've seen before include "Powerful strokes with fist or weapon" , "Gusts - squanders" , "See 5" , "See 1" , "Impacts" .)