Deadly cannon finally changing hands (6)
I believe the answer is:
mortal
'deadly' is the definition.
(synonyms)
I cannot understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for mortal that I've seen before include "Certain to die" , "Destined to die" , "Human - transitory" , "Sound a wound is deadly" , "Causing death" .)