Estrange (8)
I believe the answer is:
alienate
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">estrange</span>' is the definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for alienate that I've seen before include "Make hostile, cause to become unfriendly" , "Eat alien in order to make hostile" , "transfer" , "Distance" , "Estrange, disaffect" .)