Friend and I leave after mum comes around (5)
I believe the answer is:
amigo
'friend' is the definition.
('friend' in Spanish)
'i leave after mum comes around' is the wordplay.
'leave' becomes 'go' (to go is to depart or leave).
'after' means one lot of letters go next to another.
'mum' becomes 'ma' (both can mean mother).
'comes around' is a reversal indicator.
'ma' reversed gives 'am'.
'i'+'go'='igo'
'igo' after 'am' is 'AMIGO'.
'and' acts as a link.
(Other definitions for amigo that I've seen before include "Mexican friend" , "Mexican's mate" , "buddy abroad?" , "friend from Barcelona" , "Friend in Spanish-speaking areas" .)