Futilely (2,2,5)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">futilely</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for to no avail that I've seen before include "Without effect" , "ineffective" , "futile ..." , "it's not helping" , "In vain" .)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">futilely</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is all the clue.<br/ ></span>