Gesture of indifference (5)
I believe the answer is:
shrug
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">gesture of indifference</span>' is the definition.<br/ ><span class="explanation-format__explanation">(a shrug indicates a lack of interest)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for shrug that I've seen before include "Indifferent gesture" , "Raise (shoulders) slightly" , "display nonchalance" , "Gesture involving the shoulders" , "Shoulder movement to show indifference or resignation" .)