Gets fed up with complicated rites (5)
I believe the answer is:
tires
'gets fed up' is the definition.
(becomes fed up or tired)
'complicated rites' is the wordplay.
'complicated' indicates an anagram (a complex or confusing ordering of the letters).
'rites' with letters rearranged gives 'TIRES'.
'with' is the link.
(Other definitions for tires that I've seen before include "Weakens" , "Grows weary of rites" , "Wearies" , "Exhausts" , "Becomes weary and in need of rest" .)