Grenoble's river
I believe the answer is:
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">grenoble's river</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I've seen this in another clue)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for isere that I've seen before include "River and department of southeast France" , "French runner" , "part of France" , "somewhere in France" , "French division" .)