Group imbibing drop of stout will get wasted (4)
I believe the answer is:
lost
'wasted' is the definition.
(similar in meaning)
'group imbibing drop of stout' is the wordplay.
'group' becomes 'lot'.
'imbibing' indicates putting letters inside (imbibe can mean to drink or absorb).
'drop of' says to take the initial letters (the smallest possible amount of the word).
The initial letter of 'stout' is 's'.
'lot' enclosing 's' is 'LOST'.
'will get' is the link.
(Other definitions for lost that I've seen before include "Mislaid or strayed" , "TV series!" , "See 10" , "Not knowing one's whereabouts" , "Not having known where one is" .)