Incurable (8)
I believe the answer is:
hopeless
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">incurable</span>' is the definition.<br/ ><span class="explanation-format__explanation">(similar in meaning)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for hopeless that I've seen before include "Despairing or futile" , "Despairing, forlon" , "With no chance of success" , "Desperate" , "Incompetent" .)