Irrelevant old female never against series (2,2,11)
I believe the answer is:
of no consequence
'irrelevant' is the definition.
I know nothing about this answer so I can't tell whether this works.
'old female never against series' is the wordplay.
I cannot quite understand how this works, but
'old' could be 'o' (abbreviation) and 'o' is found in the answer.
'female' could be 'f' (abbreviation) and 'f' is found in the answer.
'never' could be 'no' (I've seen this in other clues) and 'no' is found in the answer.
'against' could be 'con' (as in pros and cons, for and against) and 'con' is present in the answer.
'series' could be 'sequence' (sequence is a kind of series) and 'sequence' is found within the answer.
This accounts for all the letters.
This explanation may well be incorrect...
Can you help me to learn more?
(Another definition for of no consequence that I've seen is " without meaning".)