Job in hotel first filled by European (5)
I believe the answer is:
heist
'job' is the definition.
(job can mean a robbery or heist)
'hotel first filled by european' is the wordplay.
'hotel' becomes 'h' (phonetic alphabet).
'first' becomes 'ist' (ist resembles 1st).
'filled by' means one lot of letters goes inside another.
'european' becomes 'E' (abbreviation e.g. EU).
'h'+'ist'='hist'
'hist' enclosing 'e' is 'HEIST'.
'in' acts as a link.
(Other definitions for heist that I've seen before include "crime?" , "Audacious robbery" , "bank job in America?" , "Robbery (mainly US)" , "Armed hold-up (sl.)" .)