Man-made (9)
I believe the answer is:
synthetic
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">man-made</span>' is the definition.<br/ ><span class="explanation-format__explanation">(I know that man-made can be written as synthetic)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for synthetic that I've seen before include "Artificially produced" , "Affected" , "Artificially made" , "Fake" , "Manufactured, not produced naturally - say material" .)