Set up Mev's goal for City (5)
I believe the answer is:
miami
'city' is the definition.
(Miami is an example)
'set up mev's goal' is the wordplay.
'set up' is a reversal indicator (in a down clue, letters go up).
'mev's' becomes 'im' (I can't justify this - if you can you should believe this answer much more).
'goal' becomes 'aim' (aim is a kind of goal).
'im'+'aim'='imaim'
'imaim' in reverse letter order is 'MIAMI'.
'for' acts as a link.
Can you help me to learn more?
(Other definitions for miami that I've seen before include "Port in Florida" , "Popular city in SE Florida" , "Resort city in SE Florida" , "place associated with vice?" , "Sunshine city in SE Florida" .)