Sometimes heartless form of address (5)
I believe the answer is:
madam
'form of address' is the definition.
(I've seen this in another clue)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for madam that I've seen before include "precocious schoolgirl?" , "Formal address to a woman - precocious little girl" , "Woman of standing" , "Make wildly happy" , "Woman with status - girl with bad manners" .)