Spirit? Try a touch of tequila (5)
I believe the answer is:
heart
'spirit?' is the definition.
(heart can mean spirit or personality)
'try a touch of tequila' is the wordplay.
'try' becomes 'hear' (as in to try someone in court or hear their case).
'a touch of' says to take the initial letters.
The first letter of 'tequila' is 't'.
'hear'+'t'='HEART'
(Other definitions for heart that I've seen before include "Vital part" , "show enthusiasm" , "It's in the chest" , "Red card" , "the name of a prison in Midlothian!" .)