Tablet quietly makes one sick (4)
I believe the answer is:
pill
'tablet' is the definition.
(synonyms)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for pill that I've seen before include "Form of medicine" , "Pellet of medicine" , "Medicinal pellet" , "Dreadful person" , "Lozenge" .)