Taking off clothes, Richard Osman stirred drink (10)
I believe the answer is:
maraschino
'drink' is the definition.
(maraschino is a kind of drink)
'taking off clothes richard osman stirred' is the wordplay.
'taking off clothes' indicates the central letters (letters which clothe the word are removed).
'stirred' indicates anagramming the letters.
The central letters of 'richard' are 'ichar'.
'ichar'+'osman'='icharosman'
'icharosman' anagrammed gives 'MARASCHINO'.
(Another definition for maraschino that I've seen is " Harmonicas (anag) - cherry liqueur".)
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