Terminus open in Telford deserted surprisingly (3,5)
I believe the answer is:
end point
'terminus' is the definition.
(thesaurus)
'open in telford deserted surprisingly' is the wordplay.
'deserted' says to hollow out the word (remove centre letters) (middle letters must vacate or desert the word).
'surprisingly' indicates an anagram (a surprising ordering of the letters).
'telford' with its middle removed is 'td'.
'open'+'in'+'td'='openintd'
'openintd' anagrammed gives 'END POINT'.
(Other definitions for end point that I've seen before include "stop appearing here?" , "Final stage of a process" .)