They take temporary charge of toilets (7)
I believe the answer is:
regents
'they' is the definition.
Both the definition and answer are plural nouns.
Perhaps you can see a link between them that I don't see?
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for regents that I've seen before include "They rule on behalf of monarchs" , "They have leading roles" .)