Think about the East river! (5)
I believe the answer is:
meuse
'river' is the definition.
(Meuse is an example)
'think about the east' is the wordplay.
'think' becomes 'muse' (to muse on something is to think about it).
'about' indicates putting letters inside.
'the east' becomes 'E' (abbreviation).
'muse' going around 'e' is 'MEUSE'.
(Another definition for meuse that I've seen is " Dept of NE France".)
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