Young lady ignoring large fool (3)
I believe the answer is:
ass
'fool' is the definition.
(both can mean a stupid person)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for ass that I've seen before include "Braying animal" , "Dolt" , "Charlie" , "Dipstick" , "Pompous person" .)