A funny programme starts in early September, anyhow (2,2,5)
I believe the answer is:
as it comes
'anyhow' is the definition.
(both can mean in any way)
'a funny programme starts in early september' is the wordplay.
'funny programme' becomes 'sitcom' (sitcom is a kind of programme. I am not sure about the 'funny' bit.).
'starts in' suggests taking the first letters.
The first letters of 'early september' is 'es'.
'a'+'sitcom'+'es'='AS IT COMES'
Can you help me to learn more?
(Other definitions for as it comes that I've seen before include "however produced" , "in no particular order" , "the way it's made" .)