Among others, General Sherman's oddly targeted (4)
I believe the answer is:
tree
'among others general sherman's' is the definition.
(General Sherman is an ancient tree in the US)
'oddly targeted' is the wordplay.
'oddly' indicates alternate letters (letters in the odd-numbered positions are used).
The alternate letters of 'targeted' are 'TREE'.
(Other definitions for tree that I've seen before include "Laurel, perhaps" , "elder, maybe" , "embraced by environmentalist?" , "Holly, perhaps" , "eg Cedar" .)