Antagonism in place after work (10)
I believe the answer is:
opposition
'antagonism' is the definition.
(thesaurus)
'place after work' is the wordplay.
'place' becomes 'position' (positioning is a kind of placing**).
'after' is a charade indicator (letters next to each other).
'work' becomes 'op' (abbreviation for opus).
'position' after 'op' is 'OPPOSITION'.
'in' acts as a link.
(Other definitions for opposition that I've seen before include "antagonism" , "those out of power" , "Political party" , "Enemy" , "obstruction" .)