Bedlam, perhaps, in a little shop man's running (6,8)
I believe the answer is:
Here is my best explanation:
'bedlam perhaps' is the definition.
(bedlam is a kind of mental hospital)
'a little shop man's running' is the wordplay.
'running' is an anagram indicator.
'alittleshopman' is an anagram of 'MENTAL HOSPITAL'.
'in' is the link.