Business in strife, initially, resulting in change (5)
I believe the answer is:
coins
'change' is the definition.
(thesaurus)
'business in strife initially' is the wordplay.
'business' becomes 'co'.
'initially' suggests taking the first letters.
The first letter of 'strife' is 's'.
'co'+'in'+'s'='COINS'
'resulting in' is the link.
(Other definitions for coins that I've seen before include "change" , "Metal money" .)