Came to south on lorry (6)
I believe the answer is:
struck
'came to' is the definition.
(strike can mean to arrive at something)
'south on lorry' is the wordplay.
'south' becomes 's' (abbreviation).
'on' means one lot of letters go next to another (in a down clue, letters appear on others).
'lorry' becomes 'truck' (I've seen this before).
's'+'truck'='STRUCK'
(Other definitions for struck that I've seen before include "Punched" , "Hit; stopped work" , "'Hit, slapped (6)'" , "Hit, knocked with blow" , "Female relative" .)