Cancel Times before end of issue (5)
I believe the answer is:
Here is my best explanation:
'cancel' is the definition.
(erasing is a kind of cancelling)
'times before end of issue' is the subsidiary indication.
'times' becomes 'eras' (era is a kind of time).
'before' means one lot of letters go next to another.
'end of' indicates one should take the final letters.
The final letter of 'issue' is 'e'.
(Other definitions for erase that I've seen before include "Scratch", "Remove all traces of", "Eradicate", "Cancel", "clear", "Wipe out", "Do away with", "Remove from memory", "Rub out, expunge" and "Delete".)