City reluctant at first to host a philanderer (8)
I believe the answer is:
lothario
'philanderer' is the definition.
(both can mean a womanising man)
'city reluctant at first to host a' is the wordplay.
'city' becomes 'rio' (Rio de Janeiro).
'reluctant' becomes 'loth' (if you are loth to do something you are reluctant).
'at first' says to put letters next to each other.
'to host' indicates putting letters inside (inserted letters are hosted or welcomed).
'rio' after 'loth' is 'lothrio'.
'lothrio' going around 'a' is 'LOTHARIO'.
(Other definitions for lothario that I've seen before include "Dissolute" , "Libertine or woman-chaser" , "Womaniser, philanderer" , "A literary libertine or womaniser" , "Don Juan-type character" .)