Comforts one son after do (8)
I believe the answer is:
consoles
'comforts' is the definition.
('console' can be a synonym of 'comfort')
'one son after do' is the wordplay.
'one' becomes 'sole' ('sole' can be a synonym of 'one'**).
'son' becomes 's'.
'after' is a charade indicator (letters next to each other).
'do' becomes 'con'.
'sole'+'s'='soles'
'soles' after 'con' is 'CONSOLES'.
(Other definitions for consoles that I've seen before include "Gives solace" , "Comforts about coolness" .)