Conditions at home sure will change (6)

I believe the answer is:

inures

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'conditions' is the definition.
The definition and answer can be both related to change as well as being verbs in their -s form.
Maybe there's a link between them I don't understand?

'home sure will change' is the wordplay.
'home' becomes 'in' ('he's home' can mean 'he's in').
'sure will change' becomes 'ures' (I can't justify this - if you can you should give a lot more credence to this answer).
'in'+'ures'='INURES'

'at' acts as a link.

Can you help me to learn more?

(Another definition for inures that I've seen is " Hardens or tempers".)

I've seen this clue in the Evening Standard.

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