Creator of issue removed boxing article (6)
I believe the answer is:
father
'creator of issue' is the definition.
(issue can refer to offspring)
'removed boxing article' is the wordplay.
'removed' becomes 'far' ('far' can be a synonym of 'removed').
'boxing' indicates putting letters inside ('box' can mean contain, as in to put in a box).
'article' becomes 'the' (the 'definite article' part of speech).
'far' going around 'the' is 'FATHER'.
(Other definitions for father that I've seen before include "See 1 Across" , "Male parent" , "Sire" , "Old man" , "Progenitor" .)