Died in home drunkenly clutching top of Jameson bottle (8)
I believe the answer is:
demijohn
'bottle' is the definition.
(demijohn is a kind of bottle)
'died in home drunkenly clutching top of jameson' is the wordplay.
'died' becomes 'd'.
'drunkenly' is an anagram indicator.
'clutching' means one lot of letters goes inside another.
'top of' says to take the initial letters.
The initial letter of 'jameson' is 'j'.
'in'+'home'='inhome'
'inhome' anagrammed gives 'emiohn'.
'emiohn' enclosing 'j' is 'emijohn'.
'd'+'emijohn'='DEMIJOHN'
(Other definitions for demijohn that I've seen before include "Large bottle for half-Jack?" , "Large bottle with handles covered in wickerwork" , "Large bottle in a wicker basket" , "Large bottle usually in a wicker cover" , "Large bottle with narrow neck for storing wine" .)