Dissolved substances - use lots at work (7)
I believe the answer is:
Here is my best explanation:
'dissolved substances' is the definition.
Although both the answer and definition are plural nouns, I don't see how they can define each other.
'use lots at work' is the wordplay.
'at work' indicates an anagram.
'uselots' is an anagram of 'SOLUTES'.
Can you help me to learn more?