Drop live commercial (4)
I believe the answer is:
'drop' is the definition.
('bead' can be a synonym of 'drop')
'live commercial' is the wordplay.
'live' becomes 'be' ('be' can be a synonym of 'live'**).
'commercial' becomes 'ad'.
(Other definitions for bead that I've seen before include "A bit of the rosary" , "Small ball with a hole through the middle" , "Part of a necklace" , "Spot of dew; one threaded on necklace" , "Drop, part of rosary" .)