Each new pain (4)
I believe the answer is:
ache
'pain' is the definition.
(ache is a kind of pain)
'each new' is the wordplay.
'new' is an anagram indicator.
'each' is an anagram of 'ACHE'.
(Other definitions for ache that I've seen before include "Shakespearean character" , "burn" , "Take an aspirin for it" , "A dull lingering pain" , "Dull continuous pain" .)