Female: bit of a looker (4)
I believe the answer is:
iris
This clue is a double definition.
'female' is the first definition.
(I've seen this before)
'bit of a looker' is the second definition.
(I've seen this before)
(Other definitions for iris that I've seen before include "Fleur-de-lys" , "Flower - rainbow" , "Rainbow - flag" , "Flag - part of eye" , "Film about writer _______ Murdoch" .)