Female in cast carrying one over (8)
I believe the answer is:
finished
'over' is the definition.
('finished' can be similar in meaning to 'over')
'female in cast carrying one' is the wordplay.
'female' becomes 'f' (abbreviation).
'cast' becomes 'shed' (shedding is a kind of casting**).
'carrying' is a charade indicator (letters next to each other).
'one' becomes 'i' (Roman numeral).
'shed' after 'i' is 'ished'.
'f'+'in'+'ished'='FINISHED'
(Other definitions for finished that I've seen before include "wrapped up" , "dressed" , "Ended. completed" , "Complete" , "Brought to an end" .)