Give notice a little word is misspelled (7)
I believe the answer is:
dismiss
'give notice' is the definition.
(give notice can mean to fire someone)
'a little word is misspelled' is the wordplay.
'a little' indicates a hidden word.
'DISMISS' is hidden in the letters of 'word is misspelled'.
(Other definitions for dismiss that I've seen before include "Fire - cashier" , "Remove from office" , "Cease to consider" , "Sack - send away" , "Sack - cashier" .)