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“Goodbye” upsets Isadora no end (5)

Ross

I believe the answer is:

adios

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'goodbye' is the definition.
(synonyms)

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(Other definitions for adios that I've seen before include "Goodbye (20 across)" , "Goodbye (Spanish)" , "So long, amigo" , "Au revoir, amigo!" , "Bye-bye (amigo)" .)

I've seen this clue in the Evening Standard.
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