Handed wine to limit pain (7)
I believe the answer is:
reached
'handed' is the definition.
('reach' can be a synonym of 'hand')
'wine to limit pain' is the wordplay.
'wine' becomes 'red wine' (red is a type of wine).
'to limit' is an insertion indicator (outside letters limit or restrain others).
'pain' becomes 'ache' (ache is a kind of pain).
'red' placed around 'ache' is 'REACHED'.
(Other definitions for reached that I've seen before include "Cad here (anag.)" , "Stretched or arrived" , "Attained" , "Came to (a place)" .)