Happy little woman with bottle (6)
I believe the answer is:
jovial
'happy' is the definition.
(I've seen this before)
'little woman with bottle' is the wordplay.
'little woman' becomes 'jo' (character from Little Women).
'with' is a charade indicator (letters next to each other).
'bottle' becomes 'vial' (vial is a kind of bottle).
'jo'+'vial'='JOVIAL'
(Other definitions for jovial that I've seen before include "Genial, joyous" , "Full of cheerful good humour" , "Happy and cheerful" , "Convivial" , "Cheerful, lively" .)