He has a way with a female (3)
I believe the answer is:
hen
'a female' is the definition.
(hen is a kind of female)
'he has a way' is the wordplay.
'has' means one lot of letters go next to another.
'a way' becomes 'n' (Compass direction - North**).
'he'+'n'='HEN'
'with' acts as a link.
(Other definitions for hen that I've seen before include "Insufficient in amount" , "Female lobster, fowl" , "Laying bird" , "Female bird" , "This party is for women only" .)