Crossword Genius

I fret less with files organised into spreads individually (4-10)

Ross

I believe the answer is:

self-fertilises

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'spreads individually' is the definition.
I know nothing about this answer so I cannot judge whether this works.

'i fret less with files organised' is the wordplay.
'with' says to put letters next to each other.
'organised' is an anagram indicator.
'i'+'fret'+'less'+'files'='ifretlessfiles'
'ifretlessfiles' anagrammed gives 'SELF-FERTILISES'.

'into' is the link.

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