Irrelevant old female never against series (2,2,11)
I believe the answer is:
of no consequence
'irrelevant' is the definition.
I know nothing about this answer so I can't judge whether this works.
'old female never against series' is the wordplay.
I cannot really understand how this works, but
'old' could be 'o' (abbreviation as in OT - Old Testament) and 'o' is found within the answer.
'female' could be 'f' (common abbreviation) and 'f' is found within the answer.
'never' could be 'no' (I've seen this in other clues) and 'no' is present in the answer.
'against' could be 'con' (as in pros and cons) and 'con' is located in the answer.
'series' could be 'sequence' (sequence is a kind of series) and 'sequence' is found in the answer.
No letters remain.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Another definition for of no consequence that I've seen is " without meaning".)