It makes sense in the Ruhr (5)

I believe the answer is:

essen

'in the ruhr' is the definition.
(city in the Ruhr region of Germany)

'it makes sense' is the wordplay.
'it makes' indicates anagramming the letters.
'sense' with letters rearranged gives 'ESSEN'.

(Other definitions for essen that I've seen before include "Industrial centre of the Ruhr" , "European city" , "Industrial city of northwest Germany" , "German industrial city on the Ruhr" , "German place name" .)

I've seen this clue in The Globe and Mail.

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