It would make stay with British hosts healthy one
I believe the answer is:
whalebone
'it would make stay' is the definition.
The definition suggests a singular noun which matches the answer.
'with british hosts healthy one' is the wordplay.
'with' becomes 'w' (abbreviation**).
'british' becomes 'b' (abbreviation e.g. in 'BBC').
'hosts' is an insertion indicator.
'healthy' becomes 'hale' ('hale' can be similar in meaning to 'healthy').
'w'+'b'='wb'
'wb' enclosing 'hale' is 'whaleb'.
'whaleb'+'one'='WHALEBONE'
Can you help me to learn more?
(Other definitions for whalebone that I've seen before include "It was formerly used for corset stays" , "It could make stay" , "Spoilt, over-indulged" , "Stiffener made from sea beast" .)